Yes, there ARE side effects to dog calming treats – and I learned this the hard way when my own Golden Retriever, Max, turned into a sleepy zombie after I gave him too many calming chews during a thunderstorm.
Let me tell you what you need to know.
What I’ve Seen in 10+ Years of Dog Training
Here’s the deal: calming treats can be a lifesaver for anxious pups. But like anything you put in your dog’s body, they come with potential side effects.

The Most Common Side Effects I’ve Witnessed
From working with hundreds of nervous dogs, here’s what I’ve seen:
- Drowsiness or lethargy (the most common one)
- Digestive upset (diarrhea or soft stools)
- Increased thirst or urination
- Mild behavioral changes (some dogs get MORE hyperactive)
Pro Tip: Always start with HALF the recommended dose to see how your dog reacts. I do this with every new dog I work with.
The Ingredients That Cause Problems
Not all calming treats are created equal. Here’s what you should watch for:
| Ingredient | Potential Side Effect |
|---|---|
| Melatonin | Extreme drowsiness, hormonal changes |
| L-Tryptophan | Digestive issues, serotonin syndrome (rare) |
| Chamomile | Allergic reactions in sensitive dogs |
| Valerian Root | Liver issues with long-term use |
I remember working with a Beagle named Bella whose owner didn’t know her calming treats were actually dangerous. She was lethargic for days until we switched to a gentler formula.
Want a safer approach? Check out these premium dog supplements that use natural ingredients with fewer side effects.
When Side Effects Become Serious
Call your vet IMMEDIATELY if you notice:
- Vomiting or severe diarrhea
- Difficulty breathing
- Seizures or tremors
- Complete loss of coordination

My Personal Rule: Quality Over Price
I’ve seen cheap calming treats wreak havoc. That’s why I only recommend high-quality dog treats from trusted brands.
Think about it this way: you wouldn’t eat sketchy supplements, right? Your dog deserves the same care.
Better Alternatives I Actually Use
Instead of relying solely on treats, try combining them with:
- Brain Training exercises (this program changed my life)
- Calming techniques I teach here
- A balanced diet with variety meal plans
And honestly? Sometimes anxiety is about boredom. I keep my training dogs entertained with a dog water fountain and monitor them with a pet camera when I’m not around.
The Bottom Line
Are there side effects to dog calming treats? Absolutely. But when used correctly, they’re safe for MOST dogs.
Just like you wouldn’t give your dog peanuts or bananas without checking first, don’t assume calming treats are risk-free. Read labels. Start slow. Watch for reactions.
Track your dog’s response using a dog health tracker so you can spot patterns.
And if your dog’s anxiety is severe? Consider getting an ESA letter for professional support.
Your anxious pup deserves relief – but make sure you’re giving it to them safely. Learn more about safe sweet treat options too.
Question for you: Have you noticed any side effects with your dog’s calming treats? Drop a comment below!

